Micrima is a Bristol based diagnostic imaging company founded in 2006. Micrima has developed the MARIA^® breast cancer screening system. This breast imaging system uses harmless radio-waves to detect breast cancer, unlike mammography that uses ionising radiation. MARIA^®  also requires no breast compression so is painless for women. It is a whole breast method of imaging compared to some modalities that use a handheld probe. With a handheld system, the operator needs to know where to look for a lesion. It has proven more effective than current imaging methods,particularly in dense tissue. MARIA^® has been trialled in over 400 women in the United Kingdom. Further trials are taking place at leading European centres. Currently, MARIA^® is being used in symptomatic clinics, it is hoped eventually this will be a viable alternative to mammography in breast screening.