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Exercise as a Treatment for Cancer

Written by Carolina Endara on 
27th October, 2025
Last revised by: Cancer Care Parcel
Updated: 21st January, 2026
Estimated Reading Time: 5 minutes

When it comes to health and wellness, it’s no surprise fitness takes a leading role alongside nutrition and mental well-being. Among its many well-known benefits, physical activity improves cardiovascular and metabolic health, enhances mental clarity, focus and mood. And emerging research reveals something even more powerful: exercise can play a direct role in both preventing and treating cancer.

While traditionally known as a way to support a healthy lifestyle, movement is now being studied as a form of medicine, one that has measurable effects on tumour biology and immune function.

Let’s explore how exercise can influence cancer risk, support treatment and promote resilience.

How Can Exercise Help?

Like chemotherapy, exercise places stress on the body. This temporary stress can reduce inflammation, a common precursor and promoter of cancer, and improve the body’s ability to detect and destroy abnormal cells, including those that may be cancerous. Some studies show that exercise boosts the activity of white blood cells that play a key role in the immune system’s defence against tumours. Moreover, regular physical activity has been linked to a lower risk of developing certain types of cancer, highlighting the significance of the immune system and cancer connection. By promoting a healthier, more responsive immune system, exercise may enhance the body’s natural defenses, allowing it to better combat the formation and spread of malignant cells. Incorporating exercise into a cancer prevention strategy can be a powerful way to bolster overall health and resilience.

Regular physical activity lowers levels of hormones like oestrogen, insulin, and insulin-like growth factor-1 (IGF-1), all of which, in excess, can encourage tumour growth.

Additionally, by helping to maintain mobility and a healthy weight, exercise reduces the risk of obesity, one of the biggest risk factors for cancer. Obesity is strongly linked to cancers such as breast, colon, uterine, and pancreatic cancers, among others.

On the mental health side, exercise enhances neuroplasticity, our brain’s ability to change through learning and experience, growth and reorganisation. This can support emotional resilience and improve cognitive performance, which are essential during the physical and psychological demands of cancer treatment and recovery. It also improves sleep quality, reduces anxiety, and helps manage depression, benefits that are invaluable to those facing a life-altering diagnosis.

How exercise supports the body

Which Cancers Can Exercise Benefit?

While exercise can benefit a wide range of cancers, certain types have been found to be more receptive to its positive effects. Research has shown that patients with breast and colorectal cancers, in particular, may experience enhanced recovery and improved quality of life when incorporating regular physical activity into their treatment plans. Furthermore, as more studies highlight the relationship between exercise and cancer management, many cancer myths debunked in the past are being overturned, allowing patients to make more informed decisions about their health. This increased awareness encourages a proactive approach, empowering individuals to take charge of their well-being during their cancer journey.

  • Breast Cancer: For women, particularly those who are postmenopausal, exercise helps regulate hormones like oestrogen, which can promote the growth of breast cancers. Numerous studies have shown that women who engage in regular physical activity have a lower risk of developing breast cancer, and if diagnosed, they can have a better prognosis and lower recurrence rate.
  • Colon Cancer: Exercise supports healthy bowel function and reduces inflammation in the gastrointestinal tract. It’s been shown to lower the risk of developing colon cancer and improve outcomes for those diagnosed. Regular physical activity also supports a more diverse and balanced gut microbiome, which may contribute to better immune health and reduced cancer risk.
  • Endometrial Cancer: Like breast cancer, endometrial cancer is hormone-sensitive. Exercise helps regulate insulin resistance and oestrogen levels, reducing the likelihood of excess endometrial cell growth.
  • Prostate Cancer: While more research is needed, initial studies suggest that physical activity may help slow the progression of prostate cancer, particularly by reducing treatment-related side effects such as fatigue and incontinence.
  • Lung Cancer: Although traditionally associated with smoking, lung cancer is increasingly correlated with lifestyle factors. Physical activity may reduce the risk of developing lung cancer and help improve lung function.

The evidence continues to grow, with many oncologists now considering exercise a form of adjunct therapy, one that doesn’t replace treatment but complements it.

How Does Exercise Affect Treatment?

Cancer treatments such as chemotherapy, radiotherapy, immunotherapy, and surgery can all take a heavy toll on the body. Exercise can make these treatments more effective and tolerable.

1. Increased Treatment Tolerance

Exercise strengthens the body, helping to preserve muscle mass and maintain energy levels. Increased physical resilience enables patients to complete their full course of treatment, which is crucial for optimal outcomes.

2. Improved Blood Flow and Drug Delivery

During chemotherapy, increased circulation from exercise helps deliver cancer-fighting drugs more efficiently to tumour sites. This can enhance treatment efficacy while reducing the severity of side effects.

3. Reduced Side Effects

Patients who engage in regular physical activity report fewer treatment-related issues, such as:

  • Fatigue
  • Nausea
  • Constipation
  • Neuropathy
  • Depression

4. Mitigating ‘Chemo Brain’

Chemo brain” refers to the cognitive impairment some people experience during or after chemotherapy. This includes symptoms such as memory lapses, trouble concentrating, and mental fog. Exercise stimulates brain-derived neurotrophic factor (BDNF), which supports cognitive function and neural recovery.

5. Enhanced Recovery

After surgery or treatment, staying active accelerates the recovery of physical function. It can also reduce the risk of complications such as blood clots or infections by supporting circulation and immune health.

Exercise and cancer treatment

Exercise and Recurrence Prevention

Perhaps one of the most compelling aspects of exercise is its role in recurrence prevention. For survivors of breast, colon, and endometrial cancer in particular, staying active after treatment can significantly lower recurrence rates. According to the American Cancer Society, survivors who meet or exceed recommended exercise levels (150 minutes per week of moderate-intensity activity) have better long-term outcomes.

Exercise continues to regulate hormone levels, immune function, and inflammatory responses, which contribute to cancer suppression even after visible tumours are gone.

Preventing recurrence and promoting recovery

What Exercises Are Recommended?

There is no one-size-fits-all approach, but the most effective programmes combine aerobic, strength, and flexibility training:

Aerobic Exercise (Cardio)

  • Walking
  • Jogging
  • Swimming
  • Dancing
  • Cycling

These activities strengthen the heart and lungs, support circulation, and improve stamina.

Strength Training

  • Free weights or resistance machines
  • Bodyweight exercises (push-ups, squats, lunges)
  • Resistance bands

This helps preserve or rebuild muscle mass, which can decline significantly during cancer treatment. Maintaining muscle improves metabolic function and physical independence.

Flexibility and Balance

  • Yoga
  • Tai Chi
  • Pilates
  • Stretching

These activities can relieve stiffness, improve mobility, and reduce stress, especially beneficial for those experiencing treatment-induced joint pain or fatigue.

How Much Exercise Is Enough?

The American Cancer Society and most oncology guidelines recommend:

  • At least 150 minutes per week of moderate aerobic activity, or
  • 75 minutes of vigorous activity, plus
  • Two strength training sessions per week

However, this is a general guideline; what’s most important is consistency. For some patients, walking for 10 minutes a few times a day may be the starting point.

Always consult a healthcare provider or oncologist before beginning any new exercise program, especially if treatment is ongoing or if you have existing conditions like bone metastases or cardiovascular concerns.

Barriers to Exercise During Cancer

Understandably, not everyone can or wants to exercise during treatment. Fatigue, pain, nausea, and emotional distress are real and valid barriers. That said, research suggests that even low-intensity movement can yield benefits. Something as simple as a short walk in the neighbourhood can offer psychological and physical rewards.

A supportive environment is key. Whether that’s joining a cancer fitness class, working with a rehab specialist, or exercising using online videos at home, patients are more likely to stick with a routine that feels safe, achievable, and even enjoyable.

Movement as Medicine

Exercise is not a cure for cancer, but it is powerful medicine. It enhances our natural defences, makes treatments more effective, and improves mental and physical resilience. For those living with cancer, survivors, and even those hoping to reduce their risk, staying active can empower our approach to the cancer experience.

Edited by: Katheeja Imani

Written by Carolina Endara

I love to write, capture and curate content to tell soul-stirring stories. I believe storytelling is the most powerful way we can inspire, mobilise and change the world.​ I dedicate my expertise in journalism, marketing and communications toward increasing awareness and resources for marginalised and oppressed communities around the world. No matter where my career takes me, my dream is to travel, transcend and transform the world through the art of storytelling. From working as a journalist abroad, supporting and sharing the stories of partner organisations and beneficiaries, to travelling solo across nations in search of knowledge, connection,  and myself.

We strongly advise you to talk with a health care professional about specific medical conditions and treatments.
The information on our site is meant to be helpful and educational but is not a substitute for medical advice.

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